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. 2006 Mar;22(4):323–329. doi: 10.1016/s0828-282x(06)70917-5

TABLE 2.

Multivariate logistic regression model of determinants of reported noncompliance with antihypertensive medication (n=509)

Determinant compliance Participants (n) Reported noncompliance (n) P Adjusted OR 95% CI
Study medication prescribed
 Losartan 62 6 1.00
 Angiotensin-converting enzyme inhibitor 283 78 0.023 3.04 1.17 to 7.92
 Calcium channel blocker 164 34 0.091 2.33 0.87 to 6.19
Beliefs concerning hypertension as a risk factor for other diseases
 A lot of effect 172 32 1.00
 Some effect 112 22 0.628 1.17 0.62 to 2.19
 No effect 225 64 0.007 2.00 1.21 to 3.33
Number of pills
 One or less 203 56 1.00
 Two to four 209 52 0.660 0.90 0.57 to 1.43
 More than four 97 10 0.002 0.30 0.15 to 0.64
Prior use
 New users 268 73 1.00
 Prior discontinuers (no use in past 30 days) 79 17 0.414 0.77 0.41 to 1.44
  Switchers (cause)
   Side effects with prior treatment 67 12 0.720 0.87 0.41 to 1.85
   Uncontrolled blood pressure with prior treatment 55 7 0.082 0.46 0.20 to 1.10
   Other 40 9 0.878 0.94 0.41 to 2.16
How much are you at risk of a stroke because of your hypertension if you do not do anything about it?
 No risk to moderate risk 98 25 1.00
 High risk to very high risk 365 87 0.558 1.18 0.69 to 2.02
 Do not know 46 6 0.072 0.40 0.15 to 1.09