TABLE 2.
Variable | Category (pg/mL) | OR | 95% CI | P |
---|---|---|---|---|
Baseline NT-proBNP model | ||||
Age, per year | 1.06 | 1.02 to 1.08 | 0.003 | |
Anterior myocardial infarction | 2.55 | 0.9 to 7.2 | 0.08 | |
Heart rate, per beats/min | 1.03 | 1.01 to 1.05 | 0.02 | |
Systolic BP, per mmHg | 0.99 | 0.97 to 1.00 | 0.03 | |
NT-proBNP (pg/mL) | <69 | Referent | 0.02 | |
69 to 190 | 1.32 | 0.30 to 5.81 | 0.71 | |
190 to 674 | 2.45 | 0.61 to 9.78 | 0.21 | |
>674 | 5.18 | 1.33 to 20.2 | 0.02 | |
24 h NT-proBNP model | ||||
Age, per year | 1.06 | 1.01 to 1.12 | 0.013 | |
NT-proBNP (per 1000 pg/mL) | 1.09 | 1.02 to 1.17 | 0.014 | |
72 h NT-proBNP model | ||||
Age, per year | 1.05 | 0.99 to 1.12 | 0.078 | |
Killip class greater than I | 3.52 | 0.93 to 13.3 | 0.065 | |
NT-proBNP (per 1000 pg/mL) | 1.09 | 1.00 to 1.19 | 0.039 |
Baseline model includes all patients and uses the baseline NT-proBNP. The 24 h model uses the 24 h NT-proBNP value and excludes 29 patients with an event in the first 24 h postrandomization. The 72 h model uses the 72 h NT-proBNP value and excludes 35 patients with an event in the first 72 h postrandomization. BP Blood pressure