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. 2008 Oct 14;3(10):e3399. doi: 10.1371/journal.pone.0003399

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David-Jürgens et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Examples of neuronal responses in form of post-stimulus time histograms (PSTHs) after tactile stimulation applied to the center of a RF. The number of spikes/bin (binwidth = 1 ms) is plotted against time. The red dotted line marks the time of maximal cell response (peak latency) in the PSTHs of fore- (left) and hindpaw (right) neurons of the young animal (upper panel). (A) Examples of PSTHs recorded in the fore- (left) and in the hindpaw representation (right) of a young rat (5 months). (B) Examples of PSTHs recorded in the fore- (left) and in the hindpaw representation (right) of an old rat (29 months). Response latencies were lengthened in aged animals by approximately the same amount for neurons of both representations.