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Mean (SD) plasma concentration vs. time profiles of midazolam (MDZ) and 1′-hydroxymidazolam following administration of a single dose (0.3 mg kg−1) of midazolam intravenously (n = 12; MDZ; •; 1′-hydroxymidazolam: ○), intramuscularly (n = 11; MDZ: 
, 1′-hydroxymidazolam: 
) or via the buccal cavity (n = 8; MDZ: 
, 1′-hydroxymidazolam: 
) to children with severe malaria and convulsions
