Table 7.

Association of haematological parameters with the various polymorphisms studied in ALL patients (n = 75 samples from 19 subjects)^*

Genotype	WBC (×109 l−1)	ANC (×109 l−1)	PLT (×109 l−1)
TPMT*3C heterozygote	0.012	0.003	0.864
ITPA C94→A heterozygote	0.981	1.000	0.534
ITPA IVS2+21A→C mutant†	0.618	0.702	0.003

^*Numbers represent P-values for the corresponding association adjusted as per the Bonferroni justification for multiple testing.

^†Mutant refers to any mutant (homozygote or heterozygote). ALL, acute lymphoblastic leukaemia; WBC, white blood cell count; ANC, absolute neutrophil count; PLT, platelet count; TPMT, thiopurine S-methyl transferase; ITPA, inosine triphosphatase.