Table 5.
Involuntary smoking among never tobacco users and never alcohol users and the risk of head and neck cancer, by cancer subsite
| Oral cavity | Pharynx | Larynx | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ca | Co | OR | 95 %CI | Ca | Co | OR | 95 %CI | Ca | Co | OR | 95 %CI | |
| Ever IS exposure1 | ||||||||||||
| never | 32 | 409 | 1.00 | 28 | 409 | 1.00 | 8 | 409 | 1.00 | |||
| ever at home or work | 51 | 487 | 1.17 | ( 0.68, 2.01) | 57 | 487 | 1.33 | ( 0.78, 2.26) | 18 | 487 | 2.90 | ( 1.09, 7.73) |
| Missing | 2 | 34 | 0 | 34 | 0 | 6 | ||||||
| P for heterogeneity | 0.52 | 0.67 | 0.52 | |||||||||
| Duration of IS exposure at home2 | ||||||||||||
| never | 26 | 477 | 1.00 | 14 | 477 | 1.00 | 13 | 421 | 1.00 | |||
| 1-15 years | 8 | 103 | 2.27 | ( 0.84, 6.10) | 8 | 103 | 2.83 | ( 1.03, 7.81) | 3 | 98 | 2.01 | ( 0.43, 9.36) |
| >15 years | 10 | 130 | 1.37 | ( 0.56, 3.35) | 9 | 130 | 4.15 | ( 1.50,11.47) | 7 | 116 | 1.85 | ( 0.53, 6.49) |
| Missing | 2 | 65 | 1 | 65 | 1 | 22 | ||||||
| P for trend | 0.44 | <.01 | 0.28 | |||||||||
| P for heterogeneity | 0.18 | 0.92 | 0.66 | |||||||||
| Duration of IS exposure at work3 | ||||||||||||
| never | 25 | 446 | 1.00 | 15 | 446 | 1.00 | 12 | 446 | 1.00 | |||
| 1-15 years | 5 | 105 | 0.90 | ( 0.26, 3.10) | 3 | 105 | 0.80 | ( 0.21, 3.13) | 4 | 105 | 2.75 | ( 0.71,10.61) |
| >15 years | 4 | 56 | 2.07 | ( 0.49, 8.72) | 4 | 56 | 3.99 | ( 1.06,15.08) | 8 | 56 | 5.45 | ( 1.69,17.52) |
| Missing | 5 | 85 | 3 | 85 | 0 | 53 | ||||||
| P for trend | 0.49 | 0.13 | <.01 | |||||||||
| P for heterogeneity | 0.71 | 0.24 | 0.40 | |||||||||
Note: Adjusted for centers, age, sex, race/ethnicity and education.
1
Included Central Europe, Tampa, Latin America, Los Angeles, and Houston studies (no Tampa study for larynx).
2
Included Central Europe, Tampa, Puerto Rico, Latin America, and Los Angeles studies (no Tampa and Puerto Rico studies for larynx).
3
Included Central Europe, Tampa, Latin America, and Los Angeles studies (no Tampa study for larynx).