Table 5.
The effect of aphidicolin on lymphocytes exposed to brevetoxin or brevetoxin and brevenal
| Treatment | N | Tail moment Mean ± SE |
|---|---|---|
| Negative control | 30 | 29.2+0.9 |
| H2O2 (2.75%) | 30 | 72.1+1.5* |
| Brevenal 1.0 μg/ml | 9 | 30.8+2.6 |
| PbTx-3 10−8 M (UNCW) | 6 | 64.0+6.4* |
| Brevenal 1.0 μg/ml 1 h before PbTx-3 10−8 M (UNCW) | 6 | 34.9+1.25 |
| Aphidicolin 10−9 M | 3 | 46.2+2.8** |
| Aphidicolin 10−9 M and PbTx-3 10−8 M (UNCW) | 3 | 63.6+4.1** |
| Aphidicolin 10−9 M and brevenal 1.0 μg/ml 1 h before PbTx-3 10−8 M (UNCW) | 3 | 64.5+1.3** |
Significantly different from the negative control, p<0.05.
Significantly different from brevenal 1.0 μg/ml, p<0.05.