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. Author manuscript; available in PMC: 2009 Jun 26.
Published in final edited form as: Neuron. 2008 Jun 26;58(6):925–937. doi: 10.1016/j.neuron.2008.05.009

Figure 2. Adaptation of mEPSCs in CA3 following chronic TTX.

Figure 2

(A) Voltage clamp recordings of mEPSCs from CA3 pyramidal cells. Holding potential, −70 mV.

(B–C) Cumulative histogram of mEPSC amplitude (B) or inter-mEPSC interval (C). n=8 each for untreated or TTX-treated group. p>0.1, K–S test for both (B) and (C).

(D) mEPSC recordings at −70 mV in the acute presence of 1 µM DCG-IV in the bath solution. Dotted line, TTX-treated.

(E–F) Cumulative histograms of mEPSC amplitude (E) or inter-mEPSC interval (F) obtained with DCG-IV in the bath. n=6 each for untreated and TTX-treated groups. *, p<10−4, K–S test.