Figure 1.
Structure of GGTI-DU40. Reprinted with permission from Peterson YK, Kelly P, Weinbaum CA, Casey PJ. A novel protein geranylgeranyltransferase-I inhibitor with high potency, selectivity, and cellular activity. J Biol Chem. 2006;281:12445–12450. © American Society for Biochemistry and Molecular Biology, Inc.