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. Author manuscript; available in PMC: 2009 Sep 1.
Published in final edited form as: Bioorg Med Chem. 2008 Jul 24;16(17):8090–8097. doi: 10.1016/j.bmc.2008.07.053

Figure 3.

Figure 3

Dose-dependent inhibition of wild-type and CCPGCC-insertion mutant PTPs. PTP activity of each wild-type and mutant was measured at the indicated FlAsH concentrations, and normalized to uninhibited (no-FlAsH) controls. Enzyme concentrations used were as follows: 100 nM for TCPTP and PTPH1; 200 nM for PTP1B, HePTP, and FAP-1; 500 nM for PTP-PEST; and 50 nM for PTPα.