Skip to main content
. Author manuscript; available in PMC: 2009 Sep 1.
Published in final edited form as: Bioorg Med Chem. 2008 Jul 24;16(17):8090–8097. doi: 10.1016/j.bmc.2008.07.053

Figure 4.

Figure 4

Specific inhibition of PTPH1-816 and PTPα-406 when assayed with the phosphopeptide substrate DADEpYLIPQQG. PTP enzymes (2.5 μM) were incubated in the absence (black lines) or presence (gray lines) of FlAsH (10 μM), diluted to the final enzyme concentration noted for each panel, and assayed at pH 7.0. (A) Wild-type PTPH1 (36 nM). (B) PTPH-816 (36 nM). (C) Wild-type PTPα (140 nM). (D) PTPα-406 (180 nM).