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. Author manuscript; available in PMC: 2009 Sep 1.
Published in final edited form as: Bioorg Med Chem. 2008 Jul 24;16(17):8090–8097. doi: 10.1016/j.bmc.2008.07.053

Figure 5.

Figure 5

Time-dependent inhibition of PTPH1-816 and PTPα-406. PTP enzymes (250 nM) were incubated with FlAsH (1 μM). At the indicated time points after FlAsH addition, pNPP was added to initiate PTP activity. Percentage activity at each time point was normalized to uninhibited (no-FlAsH) controls. Data were fitted according to two-phase exponential decay using SigmaPlot 10.0. (A) PTPH1-816. (B) PTPα-406.