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. Author manuscript; available in PMC: 2008 Oct 6.
Published in final edited form as: J Immunol. 2008 Aug 1;181(3):1787–1797. doi: 10.4049/jimmunol.181.3.1787

Figure 4. Adoptive transfer of Pn14-pulsed BMDC, BMM, and PerM into naïve, WT mice.

Figure 4

APC were cultured in medium alone or pulsed with Pn14, and injected i.v. into naïve BALB/c mice (6 mice per group). Mice were boosted i.p. with free Pn14 (2 × 108 CFU/mouse) 14d following injection of APC. Another group of BALB/c mice (n=6) were immunized and boosted on d14 with free Pn14 alone. Sera were collected on the indicated days for (A) measurement of serum Ig titers. (B) Titers of secondary (d21) PspA- and primary (day 14) PPS14-specific IgG isotypes were measured from sera analyzed in “A”. The data show the geometric mean ± SEM of the individual titers. Significance (p<0.05) is indicated in the text. Representative of 2 independent experiments.