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. Author manuscript; available in PMC: 2008 Oct 6.
Published in final edited form as: J Immunol. 2008 Aug 1;181(3):1787–1797. doi: 10.4049/jimmunol.181.3.1787

Figure 7. Adoptive transfer of Pn14-pulsed BMM from WT versus MHC-II−/− or CD40−/− mice into naïve WT mice.

Figure 7

BMM obtained from (A) C57BL/6 [WT] or MHC-II−/− mice (C567BL/6 background) or (B) BALB/c [WT] or CD40−/− mice (BALB/c background) were pulsed in vitro with Pn14. BMM (i.v.) or free Pn14 (2 × 108 CFU/mouse i.p.) were then injected into naïve C57BL/6 [A] or BALB/c [B] mice (5 mice per group). All groups of mice were immunized i.p. 14d later with free Pn14 (2 × 108 CFU/mouse). Sera were collected on the indicated days for measurement of serum Ig titers. The data show the geometric mean +/− SEM of the individual titers. *Significance (p<0.05) in comparing BMM obtained from WT vs knockout mice. Both “A” and “B” are each representative of 2 independent experiments.