Table 1.

Expression of glioma-associated antigen (GAA) in pediatric brain tumor sections by immunohistochemistry

Case	Age	Gender	Diagnosisa	Site	GFAP	EphA2	IL-13Ra2	Survivin
BSG
1	5	f	Low grade	Medulla	1+	–	1+	1+
2	15	m	High-grade	Pons	2+	2+	2+	–
3	7	f	High-grade	Pons	2+	–	1+	–
4	8	f	Low-grade	Medulla	1+	–	1+	1+
5	17	m	High-grade	Pons	1+	1+	1+	2+
6	6	m	High-grade	Pons	2+	–	–	–
7	4	f	High-grade	Pons	1+	1+	1+	1+
8	7.5	f	High-grade	Pons	1+	–	1+	–
9	4	f	Low-grade	Medulla	2+	1+	1+	2+
10	7	m	High-grade	Pons	2+	1+	–	–
11	N/A		Malignant	Pons	1+	–	–	2+
12	N/A		Malignant	Pons	1+	–	–	1+
13	N/A		Malignant	Pons	1+	–	–	2+
14	4.9	m	Low-grade	Medulla	1+	2+	2+	–
15	0.7	m	Low-grade	Pons	1+	2+	1+	–
NBSG
1	1.2	f	gbm	Temporofrontal	1+	2+	1+	1+
2	1.2	f	aa	Thalamus	1+	1+	–	–
3	16.7	f	aa	Frontoparietal	1+	2+	1+	1+
4	0.8	f	Low-grade	Frontal	1+	2+	2+	2+
5	1.4	f	aa	Basal ganglia	1+	2+	N/A	1+
6	15.6	m	aa	Frontal	1+	2+	N/A	1+
7	18	f	gbm	Frontal	1+	1+	N/A	–
8	11.5	m	Low-grade	Parieto-frontal	1+	2+	1+	1+
9	9.5	m	Low-grade	Parietal	1+	1+	1+	–
10	12.9	m	gbm	Thalamus	1+	2+	1+	1+
11	6.5	m	Low-grade	Frontal	1+	2+	1+	1+
12	6.3	f	gbm	Parietofrontal	1+	1+	–	–

N/A, information not available

^aBecause of the small sizes of many of the specimens, histological diagnoses of the brainstem gliomas are broadly characterized into low-grade and high-grade lesions—no attempt was made to distinguish presumptive grade III (AA) from grade IV (GBM) tumors