Table 2.
Glioma-associated antigen (GAA) expression in brain stem (BS) and non-brain stem (NBS) pediatric gliomas Diagnosis No. of patients EphA2
| Diagnosis | No. of patients | EphA2 −/1+/2+ | IL-13Rα2 −/+/++ | Survivin −/1+/2+ |
|---|---|---|---|---|
| BS LGG | 5 | 2/1/2 | 0/4/1 | 2/2/1 |
| BS HGG | 10 | 6/3/1 | 5/4/1 | 5/2/3 |
| NBS LGA | 4 | 0/1/3 | 0/3/1 | 1/2/1 |
| NBS AA | 4 | 0/1/3 | 1/1/0a | 1/3/0 |
| NBS GBM | 4 | 0/2/2 | 1/2/0a | 2/2/0 |
BS, brain stem; NBS, non-brain stem; LGG, low grade glioma; HGG, high grade glioma; LGA, low grade astrocytoma; AA, anaplastic astrocytoma, GBM; glioblastoma multiforme
a
There were one GBM and two AA cases that were not evaluated for IL-13Rα2 due to the limited number of slides