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. Author manuscript; available in PMC: 2009 Aug 1.
Published in final edited form as: Bioconjug Chem. 2008 Jul 12;19(8):1579–1587. doi: 10.1021/bc800110y

Figure 3.

Figure 3

Left panel: cellular retention and internalization of 111In-CHX-A” DTPA-Z2395-C by HER2-expressing SKOV-3 ovarian carcinoma cell line after inrerrupted incubation. Right panel: percentage of non-degraded conjugate in cell culture media (high-molecular-weight fraction in size-exclusion chromatography using NAP-5 columns) as a function of time after interrupted incubation and media change. Data presented as an average from three cell culture dishes ± SD. Error bars may be not seen since they are smaller than point symbols.