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. Author manuscript; available in PMC: 2009 Jul 15.
Published in final edited form as: Clin Cancer Res. 2008 Jul 15;14(14):4672–4680. doi: 10.1158/1078-0432.CCR-08-0087

Figure 2. Breast tumor tissue from Pisa#88 proband displays LOH at the BRIP1 locus.

Figure 2

Chromatograms of tumor and normal breast tissue DNA from Pisa#88 index individual. Loss of the wild type allele with retention of the mutant one is evident in the tumor sequence (upper panel). Normal tissue (lower panel) shows both mutated and wt alleles (an asterisk marks the beginning of the overlapping sequences).