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. Author manuscript; available in PMC: 2009 Aug 5.
Published in final edited form as: Alcohol Clin Exp Res. 2008 Jun 28;32(8):1479–1492. doi: 10.1111/j.1530-0277.2008.00715.x

Fig. 6.

Fig. 6

Effects of MK-801 on sensitivity to the ataxic, hypothermic and sedative/hypnotic effects of EtOH following pretreatment with Ro 25-6981 in C57BL/6J mice. (A) Rotarod learning. (B) MK-801 dose-dependently potentiated EtOH-induced ataxia regardless of Ro 25-6981 pretreatment. (C) MK-801 did not alter EtOH-induced hypothermia regardless of Ro 25-6981 pretreatment. (D) MK-801 dose-dependently potentiated EtOH-induced sedation/hypnosis regardless of Ro 25-6981 pretreatment. n = 5 to 8/genotype/treatment. V = vehicle, MK = MK-801, Ro (1) = 1 mg/kg Ro 25-6981, Ro (3) = 3 mg/kg Ro 25-6981, Ro (10) = 10 mg/kg Ro 25-6981.