Table 1.
Summary of the physico-chemical properties of cross-linked (PLL/HA)12 films for EDC varied between 5 and 100 mg/mL (EDCx means that EDC final concentration is x mg/mL). Young’s modulus was determined by AFM nano-indentation experiments [31], film roughness was determined from AFM images of film topography. Serum adsorption was measured by quartz crystal microbalance. Film thickness remained constant at ~1μm for all conditions.
| Type of film | Native | EDC5 | EDC10 | EDC30 | EDC50 | EDC100 |
|---|---|---|---|---|---|---|
| Young’s modulus E0 (kPa) * | 3 | 99 | 162 | 301 | 354 | 382 |
| Fold increase | 1 | ~ × 33 | ~ × 54 | ~ × 100 | ~ × 118 | ~ × 127 |
| Roughness (nm) * | 1.1 ± 0.3 | NA | 3.8 ± 0.5 | 5.8 ± 0.4 | 7.1 ± 1.4 | 7.4 ± 0.2 |
| Serum adsorption (ng/cm2) | 1947 | NA | 88 | 62 | 44 | 177 |
*
Values taken from ref [24].