Figure 4.

Airway hyperresponsiveness was assessed by whole-body plethysmography by measuring Penh after methacholine exposure in mice inoculated with M. pneumoniae (Mp) and treated with clarithromycin alone, dexamethasone alone, combined therapy, or placebo for 6 days (treatment began 1 day after inoculation). Bars represent results from seven to ten mice per treatment group at each time point from repeated experiments. Values shown are the means ± standard deviations (error bars). *, p < 0.05 between the two specified treatment groups at the time point by One Way ANOVA followed by pairwise multiple comparisons.