Table III.
Dose reduction index for CP-4055 combined with gemcitabine in HL-60 cells.
Dose reduction index1 | ||
---|---|---|
Fraction affected | CP-4055 | Gemcitabine |
0.1 | 2.2 | 1.4 |
0.2 | 3.3 | 1.6 |
0.3 | 4.9 | 1.9 |
0.4 | 6.9 | 2.4 |
0.5 | 9.8 | 3.0 |
0.6 | 14.2 | 3.8 |
0.7 | 21.5 | 4.7 |
0.8 | 35.7 | 5.8 |
0.9 | 71.8 | 6.6 |
Combined in a molar ratio of 400:1 (CP-4055:Gemcitabine).