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. 2008 Apr 8;49(4):786–797. doi: 10.1080/10428190801935752

Table III.

Dose reduction index for CP-4055 combined with gemcitabine in HL-60 cells.

Dose reduction index1
Fraction affected CP-4055 Gemcitabine
0.1 2.2 1.4
0.2 3.3 1.6
0.3 4.9 1.9
0.4 6.9 2.4
0.5 9.8 3.0
0.6 14.2 3.8
0.7 21.5 4.7
0.8 35.7 5.8
0.9 71.8 6.6
1

Combined in a molar ratio of 400:1 (CP-4055:Gemcitabine).