TABLE 2.
Lutein and Zeaxanthin Intake Group | ||||
---|---|---|---|---|
Low | --------------------------High-------------------------- | |||
Median intake of LZ [range] (mg/d) | 0.8 [0.3-1.1] |
2.6 [2.0-10.7] |
||
Referent | N (with outcome) | Age-adjusted model | Multivariable-adjusted model1 | |
Overall Nuclear Cataract (nuclear sclerosis score ≥ 4 and/or cataract |
1.00 | 1802 (733) | 0.77 (0.62-0.96) | 0.81 (0.65-1.01) |
Nuclear Sclerosis Score ≥ 4 | 1.00 | 1571 (451) | 0.79 (0.62-1.00) | 0.80 (0.62-1.02) |
Odds ratios are adjusted for age (continuous), smoking status at WHI Baseline (never, past, current), iris pigmentation (dark brown, light brown, green, or blue), physical activity (METs), multivitamin use at CAREDS baseline (>2y vs. non-user), hormone replacement therapy use at WHI-Baseline (never, past, current), pulse pressure at WHI-Baseline (continuous), body mass index at WHI-Baseline (weight in kg/height in m2)