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. 2008 Oct 10;283(41):27810–27819. doi: 10.1074/jbc.M804681200

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Copyright © 2008, The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 6. — D-NAAM-induced longevity requires Sir2. Survival curves of male (left panel) and female (right panel) adult flies expressing D-NAAM⁴² using the elav-Gal4 driver in control and Sir2 null background. Genotypes: wild type control: w¹¹¹⁸; D-NAAM overexpression: w¹¹¹⁸;UAS-D-NAAM⁴²/elav-Gal4; Sir2 null: w¹¹¹⁸; Sir2^4.5/Sir2^5.26; D-NAAM overexpression in Sir2 null: w¹¹¹⁸;Sir2^4.5/Sir2^5.26;UAS-D-NAAM⁴²/elav-Gal4; D-NAAM insertion control in Sir2 null: w¹¹¹⁸; Sir2^4.5/Sir2^5.26;UAS-D-NAAM⁴²/+; elav-Gal4 insertion control in Sir2 null: w¹¹¹⁸;Sir2^4.5/Sir2^5.26;elav-Gal4/+.