TABLE 2.

Summary of nonlinear regression analysis results for the glycine concentration responses in MTS-exposed WT and E53C GlyRs EC₅₀, Hill slope (n_H), and maximal current amplitude (I_max) are presented as mean ± S.E. from four different oocytes (as shown in Fig. 2). Statistical significance from unexposed GlyRs (WT or E53C) was assessed using one-way analysis of variance with Dunnett's post-test.

Receptor	MTS reagent
		No MTS			MTSES			MTSEH			MTSEA			MTSET
	EC50	nH	Imax	EC50	nH	Imax	EC50	nH	Imax	EC50	nH	Imax	EC50	nH	Imax
WT	91 ± 7	2.1 ± 0.2	16813 ± 3412	96 ± 12	1.8 ± 0.2	14625 ± 1650	89 ± 8	2.1 ± 0.3	10625 ± 881	88 ± 5	1.7 ± 0.2	13125 ± 2157	94 ± 20	2.1 ± 0.3	15875 ± 2154
E53C	544 ± 67	1.3 ± 0.3	10138 ± 1887	189 ± 31a	1.6 ± 0.2	10813 ± 2672	1250 ± 165	1.3 ± 0.2	10063 ± 1861	865 ± 48	1.5 ± 0.1	8450 ± 2913	600 ± 114	1.4 ± 0.1	13713 ± 3000

^ap < 0.05