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The total number of animals used, in each strain and in each group, is shown in Table 1. The cohort in which each group was studied is shown in parenthesis.
| Dose (mg/kg) | C57BL/6J | 129P3/J |
|---|---|---|
| 0 | n =14 (cohorts 1,4,7) | n =17 (cohorts 2, 3, 5, 6) |
| 1.25 | n = 6 (cohort 7) | n = 12 (cohorts 5, 6) |
| 2.5 | n = 6 (cohort 7) | n = 12 (cohorts 5, 6) |
| 5 | n = 9 (cohorts 1,4) | n = 9 (cohorts 2, 3) |
| 10 | n = 10 (cohorts 1,4) | n = 10 (cohorts 2, 3) |
| 20 | n = 10 (cohorts 1,4) | n = 10 (cohorts 2, 3) |
