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. Author manuscript; available in PMC: 2009 Oct 1.
Published in final edited form as: J Immunol. 2008 Oct 1;181(7):4613–4620. doi: 10.4049/jimmunol.181.7.4613

Figure 4.

Figure 4

Despite higher IL-4 and IL-10 production by BALB/c derived T cells, both strains are similarly capable of IFN-γ, IFN-γR, and Tbet expression. At various time points after stimulation was ceased, the culture supernatants of activated T cells were analyzed by ELISA and at each sampling, BALB/c derived T cells activated in vitro with anti-CD3/anti-CD28 make levels of IFN-γ similar to C57BL/6 (A) but T cells of BALB/c mice made significantly more IL-10 and IL-4 (B, C). Additionally T-bet and IFN-γR mRNA levels were found to be comparable in activated T cells of both groups by RT-PCR (D and E, respectively). Data are presented as the mean results from 2−3 independent experiments (+/−SEM). *= a P value < 0.05.