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. Author manuscript; available in PMC: 2008 Oct 6.
Published in final edited form as: Org Lett. 2006 Mar 30;8(7):1395–1398. doi: 10.1021/ol060181v

Table 1.

Desymmetrization of meso-diester 1a

graphic file with name nihms62964t1.jpg
entry ligand convb (%) % eec
1 L1 80 28.7 (−)
2 L2 82 48.1 (+)
3 L3 70 68.4 (+)
4 L5a 82 81.3 (−)
5 L5b 50 10.8 (−)
a

Reactions were run using [Pd(alllyl)Cl]2 (1 mol %) with a monodentate ligand (4 mol %) in THF at 0 ° C for 2 h.

b

Determined by 1H-NMR.

c

Determined using Daicel Chiralpak AD.