Table 1.

The localization of the phosphorylation sites relevant for arrestin binding on the cytoplasmic elements of different GPCRs

Cytoplasmic element	Receptor	References
C-terminus	Chemokine receptors CCR5	Huttenrauch et al., 2002; Kraft et al., 2001
	Chemokine receptor CCR7	Kohout et al., 2004
	Angiotensin II receptor type 1A	Qian et al., 2001
	Thyrotropin-releasing	Hanyaloglu et al., 2001
	hormone receptor
	Parathyroid hormone receptor	Vilardaga et al., 2002
	N-formyl peptide receptor	Key et al., 2003
	β1-Adrenergic receptor	Liang et al., 2003a
	Substance P receptor	Richardson et al., 2003
	Prostaglandin E2 receptor subtype EP4	Neuschafer-Rube et al., 2004
	Corticotropin-releasing hormone receptor type 1alpha	Teli et al., 2005
	Orexin-1 receptor	Milasta et al., 2005
	Protease-activated receptor-2	Stalheim et al., 2005
	Cysteinyl leukotriene type 1 receptor	Naik et al., 2005
	Neuropeptide Y Y1 receptor	Holliday et al., 2005
	Somatostatin receptor 2A m2 muscarinic cholinergic receptor	Tulipano et al., 2004
i3 (3rd loop)		Lee et al., 2000, Pals-Rylaarsdam et al., 1997
	α2A-adrenoceptor	Wang & Limbird, 2002
	Gonadotropin receptor	Bhaskaran et al., 2003, Kishi et al., 2002
	Dopamine receptor D1	Kim et al., 2004
	Dopamine receptor D2	Namkung & Sibley, 2004
i2 (2nd loop)	mu-opioid receptor	Celver et al., 2001, 2004, Lowe et al., 2002
i1 (1st loop)	Follitropin receptor	Kishi et al., 2002