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. Author manuscript; available in PMC: 2008 Oct 6.
Published in final edited form as: Psychopharmacology (Berl). 2008 May 29;199(4):637–650. doi: 10.1007/s00213-008-1183-y

Figure 9.

Figure 9

Locomotor with MA challenge performance ~50 days after MA administration. Animals were placed for 30 min in the locomotor apparatus used previously during the initial assessment of horizontal activity and stereotypy. Following a 30 min habituation period, animals received MA (1 mg/kg), were replaced back in the apparatus and total distance recorded for another 120 min. The Treatment main effect is shown since no effect of regimen was observed. During the first 10 min following methamphetamine, there was an increase in total distance traveled of MA-treated animals, regardless of regimen. At 40, 50–65 min post-challenge, MA-treated animals, again regardless of regimen, showed hypoactivity compared to SAL animals. (SAL-120min n = 19, MA-120min n = 19, SAL-15min n = 20, MA-15min n = 20). *p ≤ 0.05 MA vs SAL, regardless of regimen