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. Author manuscript; available in PMC: 2008 Oct 6.
Published in final edited form as: NMR Biomed. 2008 Oct;21(8):878–887. doi: 10.1002/nbm.1276

Figure 4.

Figure 4

Ratio of metabolites/total spectrum. Mean values and standard error of the mean are presented to demonstrate individual metabolites across classifications of encephalitis severity. Cr/Σ appears to be increased in all animals infected with SIV and moribund with AIDS. Glu/Σ shows the opposite trend. For the severest disease classifications, MI/Σ increases while NAA/Σ decreases. Cho/Σ does not differ significantly across the cohorts. FA captures these effects in combination, and is more powerful than traditional univariate analyses, as revealed by post hoc ANOVA (Cr/Σ: P = 0.07; NAA/Σ: P = 0.0006; Glu/Σ: P = 0.05; MI/Σ: P = 0.005; Cho/Σ: P = 0.29) uncorrected for multiple comparisons.