Figure 5.

Discordant p16:Ki-ras cooperating events in ECC4 cells. Anti-CDKN2a/p16ink4a (Panel A) and anti-cyclin D1 (Panel D) immunoblots of ECC4 and a panel of lung cancer cells with known RB status as indicated. Re-sequencing chromatograph of exon 20 RB codon 661 (Panel C) and K-ras codon 61 (Panel D) in ECC4 small-cell tumor cells.