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Effect of PGE2 on the frequency and amplitude of spontaneous EPSCs (sEPSCs) recorded in NTS. A, recordings of sEPSCs before (CTR), and during superfusion of PGE2 (200 nM) for 5 min. B, cumulative probability of the amplitude (left panel) and inter-event interval distributions (right panel). Solid lines depict control; dashed lines are data recorded during PGE2 application. PGE2 increased the inter-event interval (p < 0.01) and decreased the amplitude (p < 0.01).
