Fig. 6. Kinetic characterization of S402P RMPK.
PEP was the variable substrate. The symbols and labels are RMPK, S402P and RKPK for WT RMPK, mutant RMPK and rabbit kidney PK, respectively, in the absence of any allosteric effectors. The other symbols for S402P RMPK are: (◇), in the presence of 12 mM Phe and (■) in the presence of both 12 mM Phe and 10 mM FBP [24].