Table 2.

Relative potency expressed as milligrams of morphine necessary to produce the same effect as 1 mg oxycodone of all measures satisfying criteria for valid bioassay

Dependent measures	Relative potency	Confidence interval
Subjective measures
Addiction Research Center Inventory
BGa	3.75	3.01–4.90
LSDb	2.42	1.67–3.21
Visual analog scale
Coasting (‘spaced out’)b	2.83	1.69–4.48
Difficulty concentratingb	3.31	2.33–4.97
Dizzyb	3.16	2.25–4.56
Dreamyb	3.37	2.09–6.24
Feel badb	3.28	2.26–5.06
Floatingb	3.93	2.14–17.17
Having unpleasant bodily sensationsb	2.51	1.53–3.62
Heavy or sluggish feelingb	2.73	1.47–4.51
High (‘drug’ high)b	3.73	2.14–10.26
Lightheadedb	3.52	2.30–6.30
Nauseatedb	2.78	1.75–4.15
Sleepy (drowsy, tired)b	3.14	2.31–4.36
Tinglingb	2.04	0.35–3.57
Opiate Adjective Rating Scale
Carefreeb	2.52	0–10.63
Noddingb	3.12	1.98–5.10
Sweatingb	4.04	2.61–9.01
Drug effect/drug liking/take again
Feel drug effectb	3.31	2.57–4.39
Drug likinga	3.14	2.27–4.44
Take againa	3.33	2.25–5.35
Psychomotor/cognitive measures
DSST
Number of symbols drawna	2.97	1.87–4.69
Number of symbols drawn correctlya	3.02	1.88–4.87
Eye–hand coordination test
Seconds out of circleb	3.98	2.89–6.36
Physiological measures
Pupil size (mm)a,c	3.51	2.68–4.87
Mean relative potency	3.14

^aTrough rating analysis

^bPeak rating analysis

^cN=19; subject 7 not included (unable to obtain values for two time points)