Table 1.
Characteristics of all subjects tested by mixed lymphocyte cultures and/or ELISPOT assays.
| Recipient
|
HLA Alleles Shared With Donor
|
MLC vs. Donor PBMCs | MLC vs. DTCs | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Subject | Yearsa | Race | Sex | Donor Sex | Genetics | A | B | C | DRB1 | ISb | ||
| DIG001 | 1.7 | W | F | M | IDM | 1 | 0 | 1 | 0 | N | X | - |
| DIG007 | 5.8 | A | F | M | 22q11 | 0 | 0 | 0 | 1 | N | - | X |
| DIG010 | 5.6 | W | M | M | CHARGE | 0 | 0 | 0 | 1 | N | - | X |
| DIG012 | 5.1 | B | F | M | IDM | 0 | 0 | 1 | 0 | N | - | X |
| DIG019 | 5.0 | B | F | F | 22q11 | 1 | 0 | 0 | 1 | N | - | X |
| DIG020 | 4.2 | B | F | M | CHARGE | 0 | 0 | NT | 0 | N | - | X |
| DIG102 | 0.9 | W | M | M | 22q11 | 0 | 0 | 0 | 0 | Y | X | - |
| DIG105 | 4.2 | W | F | M | IDM | 1 | 0 | NT | 0 | Y | - | Xc |
| DIG106 | 3.9 | W | M | M | None | 1 | 1 | 1 | 0 | Y | - | X |
| DIG107 | 4.1 | W | M | M | CHARGE | 1 | 0 | NT | 0 | Y | - | X |
| DIG112 | 2.9 | W | M | M | CHARGE | 1 | 0 | 0 | 0 | Y | - | X |
| DIG120 | 1.3 | W | M | M | CHARGE | 1 | 1 | 1 | 1 | Y | - | X |
a
Years after transplantation at time sample was obtained.
b
Abbreviations: 22q11, hemizygosity at 22q11; A, Asian; B, Black; CHARGE association, coloboma, heart defect, atresia of the choanae, retardation of growth and development, genital hypoplasia, ear malformation/hearing loss; IDM, infant of a diabetic mother; IS, received peri-transplantation immunosuppression; NT, not tested; W, White
c
Performed twice.