Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Effect of time on the formation of 2,3-diOHCBZ by human recombinant CYP2C19 and CYP3A4. 3-OHCBZ (100 μM) was incubated with insect cell microsomes containing baculovirus-expressed CYP2C19 or CYP3A4 (5 pmol/100-μl incubation) at 37±0.1°C for 0–60 min and analyzed by HPLC/MS as described under “Materials and Methods”. Each data point represents the mean of duplicate determinations.
