Fig. 3.
Rapamycin strongly interferes with transformation induced by Q64L. (a) CEF were infected with Q64L, overlaid with nutrient agar containing 10 ng/ml rapamycin (right column) or solvent only (left column). After 14 days, the cultures were fixed and stained. (b) CEF were infected with the RCAS viruses expressing Q64L or the oncoprotein Jun, then seeded in nutrient agar supplemented with 10 ng/ml rapamycin (right column) or solvent only (left column) 12 days post infection and photographed on day 10 after seeding.