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. Author manuscript; available in PMC: 2009 Jan 1.
Published in final edited form as: Cardiovasc Res. 2008 Feb 26;79(1):141–149. doi: 10.1093/cvr/cvn053

Figure 2.

Figure 2

Transmembrane currents and calcium transients recorded from rabbit cardiomyocytes before and after the addition of 24 μM 4′-chlorodiazepam (4-ClDzp). (A) Representative current tracing from the same myocytes before (black line) and after (blue line) exposure to 4′-chlorodiazepam. (B) Current density for rabbit myocytes (n = 12) at 50 and 150 ms after a test pulse to 10 mV without (black bars) and with (blue bars) 4′-chlorodiazepam. (C) Representative calcium transients from the same cell in the absence (black line) and presence (blue line) of 4′-chlorodiazepam. (D) Current-voltage plot for calcium currents in the study. (E) Indo-1-mediated intracellular calcium transient recordings from the same cell under control (black line) and 4′-chlorodiazepam (blue line) conditions. (F) Peak calcium concentrations in rabbit cardiomyocytes with and without the addition of 4′-chlorodiazepam. *P < 0.05 vs. myocytes under control conditions .