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. Author manuscript; available in PMC: 2009 Jul 1.
Published in final edited form as: J Pharmacol Exp Ther. 2008 Apr 25;326(1):286–295. doi: 10.1124/jpet.108.139675

Figure 2.

Figure 2

Inhibition of [125I]RTI-55 binding to hDAT by cocaine (Panel A) and SoRI-20040 (Panel B). Three concentrations of [125I]RTI-55 were each displaced by 10 concentrations of cocaine or SoRI-20040. The data, expressed as percentage inhibition, were combined and analyzed for the best-fit estimates of the EMAX and EC50 (See Table 1) as described under Materials and Methods. Each point is the mean ± S.D. (n=3 for cocaine and n=4 for SoRI 20040).