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Effect of SoRI-9804 and cocaine on D-amphetamine induced DAT-mediated release of [3H]MPP+. Eight point dose-response curves were generated using 5 nM [3H]MPP+ in the absence and presence of the indicated test agents. The data of three independent experiments were pooled (24 data points) and fit to the dose-response equation for the best-fit estimate of the EC50 and EMAX (±SD) (Table 7).
