TABLE 2.
Baseline Clinical Characteristics by Gender
| Characteristic | Female Probands (n = 41) | Male Probands (n = 151) | P-Value |
|---|---|---|---|
| Age at diagnosis (years) | 45.3 ± 14.0 | 43.9 ± 10.9 | 0.49 |
| Confirmed familial AF | 13 (31.7) | 21 (13.9%) | 0.03 |
| Ejection fraction (%) | 61.1 ± 5.9 | 58.0 ± 9.0 | 0.02 |
| ECG characteristics in sinus rhythm | |||
| PR interval (ms) | 156.2 ± 30.1 | 179.3 ± 28.8 | < 0.001 |
| QRS duration (ms) | 93.6 ± 19.0 | 103.2 ± 20.5 | < 0.01 |
| QTc interval (ms) | 433.8 ± 29.1 | 425.9 ± 30.2 | 0.15 |
| QRS axis (°) | 25.2 ± 56.5 | 24.3 ± 44.1 | 0.91 |
| Ventricular rate (bpm) | 83.2 ± 33.9 | 69.6 ± 16.7 | < 0.001 |
| Type of AF | 0.15 | ||
| Paroxysmal | 29 (76.3) | 94 (64.4) | |
| Persistent | 4 (10.5) | 37 (25.3) | |
| Permanent | 5 (13.2) | 15 (10.3) | |
| Symptoms | |||
| Palpitations | 23 (88.5) | 48 (64.0) | 0.02 |
| Awakened by palpitations at night | 16 (61.5%) | 24 (32.0) | 0.01 |
| Dyspnea | 22 (84.6) | 58 (75.3) | 0.33 |
Continuous variables are presented as mean ± SD; categorical variables are presented as no. (%).