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. 2008 Oct 17;3(10):e3447. doi: 10.1371/journal.pone.0003447

Figure 4. Knockdown of PP2A catalytic subunit inhibits FGF-induced p107 dephosphorylation.

Figure 4

RCS cells were infected with retroviruses encoding either 2 different sequences specific for the α-isoform of PP2A-C subunit (shRNA1 and shRNA2) or scrambled shRNA and treated with FGF1. 20 µg of total protein were subjected to SDS-PAGE for inmmunodetection of (A) PP2A-C or (B) p107. (C) Percentage cells labeled by BrdU in the cell lines with knockdown of PP2A-Cα upon FGF treatment.