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. 2008 Nov 7;4(11):e1000206. doi: 10.1371/journal.pcbi.1000206

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Parter et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Mutual information (y-axis) between the environment (goal) and the genomic content at each position of an evolved MVG circuit (x-axis). Two positions (positions 28 and 31) have high mutual information and are defined as genetic triggers which facilitate circuit's adaptation for goals G3 and G2 respectively. (B) Same as in (A), but at three time points along evolution: beginning, middle and end of evolution. (C) as in (A), but for the RNA model. The x-axis is labeled with the parenthesis notation for RNA secondary structure. (D) Genetic triggers of (C) placed on the structure of the evolved MVG RNA molecule.