Figure 7. KIS-L is not a global regulator of H3K4 methylation.
The distribution of H3K4me2 (A, C, red), KIS-L (B, D, F and H, green), and H3K4me3 (E, G, red) on salivary gland polytene chromosomes isolated from wild-type (A, B, E and F) and kisk13416 (C, D, G and H) larvae were detected by indirect immunofluorescence microscopy. The loss of KIS-L function does not cause obvious changes in the overall level or distribution of either H3K4me2 or H3K4me3.