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. 2008 Sep 30;105(40):15564–15569. doi: 10.1073/pnas.0804249105

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© 2008 by The National Academy of Sciences of the USA

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Fig. 2. — Body weights over time of R6/2^300Q transgenic (A) and WT (B) mice throughout HDACi 4b treatment. Symbols represent mean body weight ± SEM in vehicle-treated mice (open symbols) and HDACi 4b–treated mice (filled symbols). R6/2^300Q transgenic mice treated with HDACi 4b weighed significantly more than vehicle-treated R6/2^300Q mice as determined by two-way ANOVA (P < 0.0001). (C) Effect of HDACi 4b treatment on overall brain weights of WT and R6/2^300Q transgenic mice. Significant differences were determined by one-way ANOVA and Student's t test. ***, P < 0.001; *, P < 0.05.