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Development of the CVG in E10.5–E11.5 control (A and B), Foxg1-Cre KO (C and D) and Pax2-Cre KO (E and F) embryos. Whole-mount ISH with a NeuroD probe on E10.5 embryos (A, C and E). IHC with a monoclonal m2H3 anti-neurofilament antibody on E11.5 sagittal sections (B, D and F). Control, Tbx1+/−, Foxg1-Cre KO, Tbx1 null/flox; Foxg1-Cre, Pax2-Cre KO, Tbx1 null/flox; Pax2-Cre tg.
