Table 1 Proportion of male (M) and female (F) subjects for HHT1, HHT2 and HHT?, with mean (SD) ages.
| HHT1 | HHT2 | HHT? | ||||
|---|---|---|---|---|---|---|
| Probands and family | ||||||
| No. of subjects (M:F ratio) | 735 (0.74) | 216 (0.77) | 175 (0.68) | |||
| Mean age (SD), years | 44.8 (17.2) | 46.2(16.6) | 47.8 (18.1) | |||
| HHT present (M:F ratio) | 380 (0.74) | 128 (0.71) | 76 (0.58) | |||
| Mean age (SD), years | 48.4 (18.2) | 51.2 (16.2) | 53.7 (15.5) | |||
| HHT possible (M:F ratio) | 84 (0.83) | 25 (1.27) | 60 (0.67) | |||
| Mean age (SD), years | 40.0 (16.8) | 38.0 (14.8) | 43.8 (20.9) | |||
| HHT absent (M:F ratio) | 271 (0.73) | 63 (0.75) | 39 (0.95) | |||
| Mean age (SD), years | 41.2 (14.7) | 39.1 (16.8) | 42.6 (15.2) | |||
| HHT present | ||||||
| No. of subjects | 380 | 128 | 76 | |||
| No. of families | 63 | 40 | 44 | |||
| Members per family | 6 | 3.2 | 1.7 | |||
| Men | 161 (42.4%) | 53 (41.4%) | 28 (36.8%) | |||
| Women | 219 (57.6%) | 75 (58.6%) | 48 (63.1%) | |||
| Mean age (SD), years | 48.4 (18.2) | 51.2 (16.2) | 53.7 (15.5) | |||
| Mean age M (SD), years | 47.9 (18.8) | 53.5 (13.6) | 51.9 (13.6) | |||
| Mean age F (SD), years | 48.8 (17.7) | 49.7 (17.7) | 54.8 (16.5) |
Family members with a clinical and or genetic certain diagnosis, ascertained from the database, are shown. The "HHT presentW group consists of patients with a clinically and or genetically confirmed diagnosis. Patients were deemed "possible" when two of the four criteria were present. Patients with HHT in combination with juvenile polyposis were excluded.