Figure 3 Genomewide (A) and chromosome 10q23 (B) linkage analyses. (A) SNP genotyping and haplotype based linkage analysis by Varia reveal a 7 Mb region on chromosome 10 (83–90 Mb) with LOD scores above 2.0. Each haplotype block contains a list of possible haplotypes as well as a pattern of co‐transmission among the individuals (black lines) genotyped. The maximum haplotype based LOD score is 2.664 (θ = 0) at 84 Mb. (B) A sliding map of nine microsatellite markers was used to calculate multipoint linkage analysis between markers D10S569 and D10S536. Combined genotyping data from families 1 and 2 were used.