Table 1.

Summary of recommendations

Study design	Data processing	Analyses
Use interaction or parametric interaction designs	Compare and select the best normalization algorithms	Assess effects within groups; control for group differences in performance
Include sufficient sample sizes in each group (equal numbers or more in older adult group)	Use appropriate reference anatomical templates	Test for equal variance between groups
Include appropriate controls for group differences in HRFs (functional or hypercapnia)	Specify or adjust regions of interest on individual participants regardless of age	Use appropriate statistical models (i.e. nonparametric, multilevel, etc.)